Biology:Puumala virus

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Puumala virus
Virus classification
Group:
Group V ((−)ssRNA)
Order:
Family:
Genus:
Species:
Puumala virus

Puumala virus (PUUV) is a species of orthohantavirus. Humans infected with the virus may develop a haemorrhagic fever with renal syndrome (HFRS) known as nephropathia epidemica. Puumala virus HFRS is lethal in less than 0.5% of the cases.[1]

Puumala virus is named after a municipality in Finland . The virus is found predominantly in Scandinavia and Finland , although it has also been reported elsewhere in Northern Europe, Poland and Russia . Because the bank vole (Myodes glareolus) acts as a reservoir for the virus, nephropathia epidemica cases track with the vole population in a three- to four-year cycle. Humans are infected through inhalation of dust from vole droppings.[2]

It has been theorized that Puumala virus, unlike other members of the genus Hantavirus, may also have lethal effects on its rodent host.[3]

In August 2014 was announced the death of an Israeli researcher studying the behavior of the bank vole in Finland. She had been affected by the Puumala virus which caused a complete breakdown of her immune system.[4]

Puumala virus was discovered and named in 1980 by researchers in Finland.[5]

References

  1. Discertation for doctoral exam; Distribution of Puumalavirus in Sweden , by C. Ahlm, second paragraph; latest access 2012-06-04
  2. "Patterns of Puumala virus infection in Finland". Euro Surveill 8 (1): 9–13. January 2003. PMID 12631978. http://www.eurosurveillance.org/em/v08n01/0801-222.asp. 
  3. "Endemic hantavirus infection impairs the winter survival of its rodent host". Ecology 88 (8): 1911–6. August 2007. doi:10.1890/06-1620.1. PMID 17824420. https://www.researchgate.net/publication/6016866_Endemic_hantavirus_infection_impairs_the_winter_survival_of_its_rodent_host. 
  4. קלנר, ירון (8 July 2014). "קרן חקרה מכרסמים - שגרמו למותה מנגיף אלים". http://www.ynet.co.il/articles/0,7340,L-4555889,00.html. 
  5. Brummer-Korvenkontio, M.; Vaheri, A.; Hovi, T.; Von Bonsdorff, C. H.; Vuorimies, J.; Manni, T.; Penttinen, K.; Oker-Blom, N. et al. (1980). "Nephropathia epidemica: detection of antigen in bank voles and serologic diagnosis of human infection". The Journal of Infectious Diseases 141 (2): 131–134. doi:10.1093/infdis/141.2.131. PMID 6102587. 

Wikidata ☰ Q29002553 entry