Biology:Sialidase-4
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.[1]
Function
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids.[1]
Interactions
Sialidase-4 has been shown to interact with phospholipid scramblase 1.[2]
References
- ↑ 1.0 1.1 "Entrez Gene: NEU4 sialidase 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=129807.
- ↑ "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
Further reading
- "Identification and expression of Neu4, a novel murine sialidase.". Gene 321: 155–61. 2004. doi:10.1016/j.gene.2003.08.005. PMID 14637003.
- "Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family.". Genomics 83 (3): 445–53. 2004. doi:10.1016/j.ygeno.2003.08.019. PMID 14962670.
- "Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells.". J. Biol. Chem. 279 (35): 37021–9. 2004. doi:10.1074/jbc.M404531200. PMID 15213228.
- "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. 2004. doi:10.1073/pnas.0404089101. PMID 15498874. Bibcode: 2004PNAS..10115724W.
- "Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages.". FEBS J. 272 (10): 2545–56. 2005. doi:10.1111/j.1742-4658.2005.04679.x. PMID 15885103.
Original source: https://en.wikipedia.org/wiki/Sialidase-4.
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