Biology:Spermosin

Spermosin (EC 3.4.21.99) is an enzyme.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

Hydrolyses arginyl bonds, preferably with Pro in the P2 position

This enzyme is isolated from the ascidian (Prochordate) Halocynthia roretzi.

References

↑ "Purification and characterization of two types of trypsin-like enzymes from sperm of the ascidian (Prochordata) Halocynthia roretzi. Evidence for the presence of spermosin, a novel acrosin-like enzyme". The Journal of Biological Chemistry 259 (5): 2900–4. March 1984. PMID 6365918.
↑ "Evidence for the participation of two sperm proteases, spermosin and acrosin, in fertilization of the ascidian, Halocynthia roretzi: inhibitory effects of leupeptin analogs on enzyme activities and fertilization". Developmental Biology 105 (1): 246–9. September 1984. doi:10.1016/0012-1606(84)90281-1. PMID 6381175.
↑ "Localization, expression, and the role in fertilization of spermosin, an ascidian sperm trypsin-like protease". Biochemical and Biophysical Research Communications 222 (2): 499–504. May 1996. doi:10.1006/bbrc.1996.0773. PMID 8670234.
↑ "Substrate specificity of ascidian sperm trypsin-like proteases, spermosin and acrosin". Molecular Reproduction and Development 45 (2): 240–3. October 1996. doi:10.1002/(SICI)1098-2795(199610)45:2<240::AID-MRD18>3.0.CO;2-4. PMID 8914083.

Spermosin at the US National Library of Medicine Medical Subject Headings (MeSH)

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v t e Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)
Digestive enzymes	Enteropeptidase Trypsin Chymotrypsin Elastase Neutrophil Pancreatic
Coagulation	factors: Thrombin Factor VIIa Factor IXa Factor Xa Factor XIa Factor XIIa Kallikrein PSA KLK1 KLK2 KLK3 KLK4 KLK5 KLK6 KLK7 KLK8 KLK9 KLK10 KLK11 KLK12 KLK13 KLK14 KLK15 fibrinolysis: Plasmin Plasminogen activator Tissue plasminogen activator Urinary plasminogen activator
Complement system	Factor B Factor D Factor I MASP MASP1 MASP2 C3-convertase
Other immune system	Chymase Granzyme Tryptase Proteinase 3/Myeloblastin
Venombin	Ancrod Batroxobin
Other	Acrosin Prolyl endopeptidase Pronase Proprotein convertases 1 2 Prostasin Reelin Subtilisin/Furin/Membrane-bound transcription factor peptidase, site 1

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)