Chemistry:Deoxyguanosine triphosphate

Deoxyguanosine triphosphate
Names
	IUPAC name 2′-Deoxyguanosine 5′-(tetrahydrogen triphosphate)
	Systematic IUPAC name O1-{[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Identifiers
CAS Number	2564-35-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16497 ;
ChEMBL	ChEMBL477486 ;
ChemSpider	58613 ;
PubChem CID	65103;
UNII	8C2O37Y44Q ;
	InChI InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1 Key: HAAZLUGHYHWQIW-KVQBGUIXSA-N ;
	SMILES O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n1cnc2c1NC(=N/C2=O)\N)C[C@@H]3O;
Properties
Chemical formula	C10H16N5O13P3
Molar mass	507.181023
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Deoxyguanosine triphosphate^[1] (dGTP) is a nucleoside triphosphate, and a nucleotide precursor used in cells for DNA synthesis. The substance is used in the polymerase chain reaction technique, in sequencing, and in cloning. It is also the competitor of inhibition onset by acyclovir in the treatment of HSV virus.^[2]

References

↑ Nelson, David L.; Cox, Michael M. (2005), Principles of Biochemistry (4th ed.), New York: W. H. Freeman, ISBN 0-7167-4339-6
↑ "Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1". Am. J. Med. 73 (1A): 14–7. July 1982. doi:10.1016/0002-9343(82)90056-0. PMID 6285704.

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Names


IUPAC name 2′-Deoxyguanosine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name O¹-{[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Identifiers
CAS Number	2564-35-4^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16497^N
ChEMBL	ChEMBL477486^N
ChemSpider	58613^Y
PubChem CID	65103
UNII	8C2O37Y44Q^Y
InChI InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1^Y Key: HAAZLUGHYHWQIW-KVQBGUIXSA-N^Y
SMILES O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n1cnc2c1NC(=N/C2=O)\N)C[C@@H]3O
Properties
Chemical formula	C₁₀H₁₆N₅O₁₃P₃
Molar mass	507.181023
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references