Chemistry:Ravuconazole
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Short description: Chemical compound
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| Formula | C22H17F2N5OS |
| Molar mass | 437.47 g·mol−1 |
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Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007.[1] The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life.[2] However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes.[3][4]
See also
- Albaconazole
- Fosravuconazole, a prodrug of ravuconazole
- Isavuconazole
References
- ↑ "Ravuconazole" (in en). AdisInsight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800006206.
- ↑ "Ravuconazole". The Aspergillus Website. http://www.aspergillus.org.uk.
- ↑ "Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole". Current Opinion in Investigational Drugs 11 (2): 165–174. February 2010. PMID 20112166.
- ↑ "Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000". Antimicrobial Agents and Chemotherapy 46 (4): 1032–1037. April 2002. doi:10.1128/AAC.46.4.1032-1037.2002. PMID 11897586.
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