Chemistry:Haloprogin
From HandWiki
Short description: Chemical compound
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| Routes of administration | Topical |
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| Formula | C9H4Cl3IO |
| Molar mass | 361.38 g·mol−1 |
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| Melting point | 113.5 °C (236.3 °F) |
| Solubility in water | Insoluble mg/mL (20 °C) |
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Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections.[1] It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.
Action
Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over-the-counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.[2]
Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[3]
References
- ↑ "Haloprogin as treatment for fungal infections". Clinical and Experimental Dermatology 4 (4): 548. December 1979. doi:10.1111/j.1365-2230.1979.tb01656.x. PMID 161212.
- ↑ "Haloprogin". Drugs@FDA. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview&DrugName=HALOTEX.
- ↑ "Haloprogin". DrugBank. University of Alberta. Nov 6, 2006. http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01011.txt.
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