Chemistry:Ro-44-3888
From HandWiki
Short description: Chemical compound
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| Formula | C18H24N4O5 |
| Molar mass | 376.413 g·mol−1 |
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Ro 44-3888 is a non-peptidic, selective and reversible glycoprotein IIb/IIIa inhibitor. It is the active metabolite of sibrafiban.[1] It was being investigated as a treatment for heart conditions, including myocardial infarctions. The development of Ro 44-3888 and sibrafiban was discontinued in 1999 following unfavorable Phase III efficacy data.
See also
References
- ↑ "Peptide diversity in drug discovery". Frontiers in drug design and discovery. 3. Saif Zone, Sharjah, United Arab Emirates: Bentham Science Publishers. 2007. p. 395-432 (414). ISBN 978-1-60805-201-1. https://books.google.com/books?id=ymeAuO0z5HAC&dq=Ro-44-3888&pg=PA414.
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