Chemistry:Picotamide

Short description: Chemical compound

Picotamide

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC03 (WHO)
Identifiers
IUPAC name 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide
CAS Number	32828-81-2 Y 80530-63-8 (monohydrate)
PubChem CID	4814
ChemSpider	4649 Y
UNII	654G2VCI4Q
Chemical and physical data
Formula	C21H20N4O3
Molar mass	376.416 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(NCc1cccnc1)c3cc(C(=O)NCc2cccnc2)c(OC)cc3
InChI InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27) Y Key:KYWCWBXGRWWINE-UHFFFAOYSA-N Y
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Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.

Further reading

• "A review of picotamide in the reduction of cardiovascular events in diabetic patients". Vascular Health and Risk Management 3 (1): 93–8. 2007. PMID 17583179.