Chemistry:Tigloidine

Tigloidine
Clinical data
Trade names	Tropigline
Identifiers
	IUPAC name (8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) (E)-2-methylbut-2-enoate;
CAS Number	495-83-0 ;
PubChem CID	5281865;
ChemSpider	16736065;
UNII	75GK1SV4EI;
KEGG	C10868;
ChEBI	CHEBI:9593;
ChEMBL	ChEMBL2107120;
Chemical and physical data
Formula	C13H21NO2
Molar mass	223.316 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC=C(C)C(=O)OC1CC2CCC(C1)N2C;
	InChI InChI=1S/C13H21NO2/c1-4-9(2)13(15)16-12-7-10-5-6-11(8-12)14(10)3/h4,10-12H,5-8H2,1-3H3/b9-4+; Key:UVHGSMZRSVGWDJ-RUDMXATFSA-N;

Short description: Chemical compound

Tigloidine is a tropane alkaloid that naturally occurs as a minor constituent of a number of solanaceous plants, including Duboisia myoporoides,^[1] Physalis peruviana,^[2] and Mandragora turcomanica.

It was formerly marketed as an antiparkinsonian drug^[3] under the trade name Tropigline.^[4]

References

↑ "383. The minor alkaloids of Duboisia myoporoides". Journal of the Chemical Society (Resumed): 1820. 1937. doi:10.1039/JR9370001820.
↑ "Biosynthesis of ticloidine in Physalis peruviana". Phytochemistry 13 (10): 2143–2144. 1974. doi:10.1016/0031-9422(74)85016-8.
↑ "Approved Names". British Medical Journal 1 (5080): 1175. 1958. doi:10.1136/bmj.1.5080.1175.
↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1663–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA1419.

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