Chemistry:Dexetimide

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Short description: Chemical compound
Dexetimide
Dexetimide.svg
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)
Identifiers
CAS Number
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IUPHAR/BPS
DrugBank
ChemSpider
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ChEMBL
Chemical and physical data
FormulaC23H26N2O2
Molar mass362.473 g·mol−1
3D model (JSmol)
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Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.[1][2]

References

  1. "A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent". Acta Psychiatrica Scandinavica 47 (4): 399–410. 1971. doi:10.1111/j.1600-0447.1971.tb03697.x. PMID 4947805. 
  2. "Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action". Psychiatria, Neurologia, Neurochirurgia 76 (4): 251–9. 1973. PMID 4581374.