Biology:BRSK1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

BR serine/threonine kinase 1 is an enzyme that in humans is encoded by the BRSK1 gene.

External links

• Human BRSK1 genome location and BRSK1 gene details page in the UCSC Genome Browser.

Further reading

• "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1". The EMBO Journal 23 (4): 833–43. Feb 2004. doi:10.1038/sj.emboj.7600110. PMID 14976552. 
• "Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function". The Journal of Biological Chemistry 279 (30): 31164–70. Jul 2004. doi:10.1074/jbc.M404728200. PMID 15150265. 
• "14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK". Journal of Cell Science 118 (Pt 23): 5661–73. Dec 2005. doi:10.1242/jcs.02670. PMID 16306228. 
• "SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release". Neuron 50 (2): 261–75. Apr 2006. doi:10.1016/j.neuron.2006.03.018. PMID 16630837. 
• "Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains". The Biochemical Journal 411 (2): 249–60. Apr 2008. doi:10.1042/BJ20080067. PMID 18254724. https://hal.archives-ouvertes.fr/hal-00478950/file/PEER_stage2_10.1042%252FBJ20080067.pdf. 
• "Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation". The Journal of Biological Chemistry 283 (22): 14946–54. May 2008. doi:10.1074/jbc.M710381200. PMID 18339622. 
• "C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest". The Journal of Biological Chemistry 284 (1): 77–84. Jan 2009. doi:10.1074/jbc.M806152200. PMID 18854318. 
• "Loci at chromosomes 13, 19 and 20 influence age at natural menopause". Nature Genetics 41 (6): 645–7. Jun 2009. doi:10.1038/ng.387. PMID 19448619. 
• "Genome-wide association studies identify loci associated with age at menarche and age at natural menopause". Nature Genetics 41 (6): 724–8. Jun 2009. doi:10.1038/ng.385. PMID 19448621. 
• "SADB phosphorylation of gamma-tubulin regulates centrosome duplication". Nature Cell Biology 11 (9): 1081–92. Sep 2009. doi:10.1038/ncb1921. PMID 19648910.