Biology:ADP—thymidine kinase
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Short description: Enzyme
| ADP-thymidine kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.118 | ||||||||
| CAS number | 82114-39-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
ADP—thymidine kinase (EC 2.7.1.118) is an enzyme that catalyzes a chemical reaction that converts thymidine to thymidine phosphate by transferring a phosphate group from the cofactor, adenosine diphosphate (ADP), which is converted to adenosine monophosphate (AMP):
- REDIRECT Template:Chemical reaction
The enzyme was characterised from cells which had been infected with Herpes simplex virus.[1]
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:thymidine 5'-phosphotransferase. Other names in common use include ADP:dThd phosphotransferase, and adenosine diphosphate-thymidine phosphotransferase.[2]
See also
- AMP—thymidine kinase, which carries out the same reaction using AMP as phosphate donor
References
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