Biology:GABRR2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Gamma-aminobutyric acid receptor subunit rho-2 is a protein that in humans is encoded by the GABRR2 gene.[1][2]
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR2 is a member of the rho subunit family.[2]
See also
References
- ↑ "Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4". Genomics 12 (4): 801–806. May 1992. doi:10.1016/0888-7543(92)90312-G. PMID 1315307.
- ↑ 2.0 2.1 "Entrez Gene: GABRR2 gamma-aminobutyric acid (GABA) receptor, rho 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2570.
Further reading
- "The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.". J. Biol. Chem. 272 (21): 13750–13757. 1997. doi:10.1074/jbc.272.21.13750. PMID 9153229.
- "Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation.". Neurosci. Lett. 255 (1): 17–20. 1999. doi:10.1016/S0304-3940(98)00696-X. PMID 9839716.
- "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3.". Biochim. Biophys. Acta 1447 (2–3): 307–312. 1999. doi:10.1016/S0167-4781(99)00167-0. PMID 10542332.
- "GABAC receptor sensitivity is modulated by interaction with MAP1B". J. Neurosci. 20 (23): 8643–8650. 2001. doi:10.1523/jneurosci.20-23-08643.2000. PMID 11102469.
- "Phosphorylation of the recombinant rho1 GABA receptor". Int. J. Dev. Neurosci. 20 (3–5): 237–246. 2002. doi:10.1016/S0736-5748(02)00037-0. PMID 12175859.
- "ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–6135. 2003. doi:10.1074/jbc.M205162200. PMID 12431995.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Molecular and physiological evidence for functional gamma-aminobutyric acid (GABA)-C receptors in growth hormone-secreting cells". J. Biol. Chem. 278 (22): 20192–20195. 2003. doi:10.1074/jbc.M301729200. PMID 12660236.
- "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–811. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. 2004. doi:10.1101/gr.2596504. PMID 15489334.
External links
- GABRR2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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