Biology:GRIN3B

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Glutamate [NMDA] receptor subunit 3B is a protein that in humans is encoded by the GRIN3B gene.

See also

• NMDA receptor

Further reading

• "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.". Neurotoxicology 19 (4–5): 683–8. 1998. PMID 9745929. 
• "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95". Science 269 (5231): 1737–40. 1995. doi:10.1126/science.7569905. PMID 7569905. Bibcode: 1995Sci...269.1737K. 
• "Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity". Ann. Neurol. 37 (3): 373–80. 1995. doi:10.1002/ana.410370314. PMID 7695237. 
• "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons". Eur. J. Neurosci. 7 (11): 2285–93. 1996. doi:10.1111/j.1460-9568.1995.tb00649.x. PMID 8563977. 
• "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase". Neurodegeneration 4 (3): 315–21. 1996. doi:10.1016/1055-8330(95)90021-7. PMID 8581564. 
• "Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120". AIDS 10 (5): 463–8. 1996. doi:10.1097/00002030-199605000-00003. PMID 8724036. 
• "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons". NeuroReport 7 (5): 1045–9. 1996. doi:10.1097/00001756-199604100-00018. PMID 8804048. 
• "HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures". Brain Res. 705 (1–2): 168–76. 1996. doi:10.1016/0006-8993(95)01166-8. PMID 8821747. 
• "Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine". Brain Res. 706 (2): 303–7. 1996. doi:10.1016/0006-8993(95)01197-8. PMID 8822372. 
• "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid". Eur. J. Neurosci. 7 (12): 2502–7. 1996. doi:10.1111/j.1460-9568.1995.tb01048.x. PMID 8845955. 
• "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548. 
• "Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase". Virology 226 (2): 362–73. 1997. doi:10.1006/viro.1996.0664. PMID 8955056. 
• "HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism". J. Biol. Chem. 273 (28): 17852–8. 1998. doi:10.1074/jbc.273.28.17852. PMID 9651389. 
• "Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats". Neuroscience 88 (2): 585–97. 1999. doi:10.1016/S0306-4522(98)00242-5. PMID 10197777. 
• "Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures". Exp. Neurol. 158 (1): 164–70. 1999. doi:10.1006/exnr.1999.7080. PMID 10448428. 
• "Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system". AIDS Res. Hum. Retroviruses 15 (16): 1461–7. 1999. doi:10.1089/088922299309973. PMID 10555109. 
• "HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity". J. Neurochem. 78 (3): 457–67. 2001. doi:10.1046/j.1471-4159.2001.00396.x. PMID 11483648. 
• "HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons". Biochem. Biophys. Res. Commun. 288 (2): 301–8. 2001. doi:10.1006/bbrc.2001.5743. PMID 11606043. 
• "Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner". J. Neurosci. 21 (23): RC185. 2002. doi:10.1523/JNEUROSCI.21-23-j0003.2001. PMID 11717388. 

External links

• GRIN3B+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)