Biology:CYP55 family

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Short description: Group of cytochrome P450 enzymes
The evolutionary divergence of the CYP superfamily collected in 1990, CYP55 is in the branch of prokaryotic CYPs

Cytochrome P450, family 55, also known as CYP55, is a cytochrome P450 family in fungi supposed to derived from horizontal gene transfer of Actinomycetes CYP105 family member in the ancestor of all Dikarya (Ascomycota and Basidiomycota).[1][2] The first gene identified in this family is the CYP55A1 from Fusarium oxysporum encoding the NADPH dependent reductase of nitrous oxide (P450nor cytochrome P450nor).[3][4]

References

  1. ↑ "Fungal cytochrome p450 monooxygenases: their distribution, structure, functions, family expansion, and evolutionary origin". Genome Biology and Evolution 6 (7): 1620–34. June 2014. doi:10.1093/gbe/evu132. PMID 24966179. 
  2. ↑ "Cytochrome P450 diversity in the tree of life". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1866 (1): 141–154. January 2018. doi:10.1016/j.bbapap.2017.05.003. PMID 28502748. 
  3. ↑ "Denitrification by the fungus Fusarium oxysporum and involvement of cytochrome P-450 in the respiratory nitrite reduction". The Journal of Biological Chemistry 266 (17): 11078–82. June 1991. doi:10.1016/S0021-9258(18)99130-1. PMID 2040619. 
  4. ↑ "The B' helix determines cytochrome P450nor specificity for the electron donors NADH and NADPH". The Journal of Biological Chemistry 277 (37): 33842–7. September 2002. doi:10.1074/jbc.M203923200. PMID 12105197. 




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