Biology:CYP6G1
From HandWiki
Short description: Protein-coding gene in the species Drosophila melanogaster
| Cytochrome P450 6g1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | Cyp6g1 | ||||||
| Alt. symbols | CYP6-like, DDT-R, Rst(2)DDT | ||||||
| Entrez | 36316 | ||||||
| HomoloGene | 59722 | ||||||
| RefSeq (mRNA) | NM_136899.4 | ||||||
| RefSeq (Prot) | NP_610743.2 | ||||||
| UniProt | Q9V674 | ||||||
| Other data | |||||||
| EC number | 1.14.-.- | ||||||
| Chromosome | 2R: 12.19 - 12.19 Mb | ||||||
| |||||||
Cyp6g1 or DDT-R is an insecticide resistance gene for resistance to DDT in Drosophila melanogaster.[1] It belongs to the cytochrome P450 family and is located in chromosome 2R.[2] Following up their earlier work, Daborn et al. 2002 find the DDT-R gene induces overtranscription of Cyp6g1, of which there are 4 duplicates.[3] They also find several substrates of Cyp6g1, namely DDT, lufenuron, and nitenpyram.[3]
References
- ↑ "Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1". Pest Management Science 64 (6): 639–645. June 2008. doi:10.1002/ps.1567. PMID 18338338.
- ↑ "Resistance evolution in Drosophila: the case of CYP6G1". Pest Management Science 73 (3): 493–499. March 2017. doi:10.1002/ps.4470. PMID 27787942.
- ↑ 3.0 3.1 "Evolution of genes and genomes on the Drosophila phylogeny". Nature (Nature Portfolio) 450 (7167): 203–218. November 2007. doi:10.1038/nature06341. PMID 17994087. Bibcode: 2007Natur.450..203C.
External links
- FlyBase Gene Report: Dmel\Cyp6g1 at FlyBase database of Drosophila genes.
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