Biology:GDF1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.[1]
GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.[2] It is found in the brain, spinal cord and peripheral nerves of embryos.[1][2]
References
- ↑ 1.0 1.1 Lee SJ (May 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". Proc. Natl. Acad. Sci. U.S.A. 88 (10): 4250–4. doi:10.1073/pnas.88.10.4250. PMID 2034669. Bibcode: 1991PNAS...88.4250L.
- ↑ 2.0 2.1 "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat. Genet. 24 (3): 262–5. March 2000. doi:10.1038/73472. PMID 10700179.
Further reading
- "Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human.". Genome Res. 8 (12): 1259–72. 1998. doi:10.1101/gr.8.12.1259. PMID 9872981.
- Lee SJ (1990). "Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily.". Mol. Endocrinol. 4 (7): 1034–40. doi:10.1210/mend-4-7-1034. PMID 1704486.
- "Correlation of inhibitor of differentiation 1 expression to tumor progression, poor differentiation and aggressive behaviors in cervical carcinoma.". Gynecol. Oncol. 114 (1): 89–93. 2009. doi:10.1016/j.ygyno.2009.03.016. PMID 19359031.
- "The family of bone morphogenetic proteins.". Kidney Int. 57 (6): 2207–14. 2000. doi:10.1046/j.1523-1755.2000.00081.x. PMID 10844590.
- Lee SJ (1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure.". Proc. Natl. Acad. Sci. U.S.A. 88 (10): 4250–4. doi:10.1073/pnas.88.10.4250. PMID 2034669. Bibcode: 1991PNAS...88.4250L.
- "Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly.". Mol. Genet. Metab. 98 (1–2): 225–34. 2009. doi:10.1016/j.ymgme.2009.05.005. PMID 19553149.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. 2004. doi:10.1038/nature02399. PMID 15057824. Bibcode: 2004Natur.428..529G.
- "Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans.". Am. J. Hum. Genet. 81 (5): 987–94. 2007. doi:10.1086/522890. PMID 17924340.
- "Chromosomal distribution of 320 genes from a brain cDNA library.". Nat. Genet. 4 (4): 381–6. 1993. doi:10.1038/ng0893-381. PMID 8401586.
 |  |
