Biology:Activin receptor
From HandWiki
| Activin types I and II receptor domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Activin_recp | ||||||||
| Pfam | PF01064 | ||||||||
| InterPro | IPR000472 | ||||||||
| PROSITE | PDOC00223 | ||||||||
| SCOP2 | 1tbi / SCOPe / SUPFAM | ||||||||
| Membranome | 1216 | ||||||||
| |||||||||
An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain and a specific hydrophilic Cys-rich ligand-binding domain.[1][2][3]
Types include:
- Activin type 1 receptors
- Activin type 2 receptors
Human proteins containing this domain
ACVR1; ACVR1B; ACVR1C; ACVR2A; ACVR2B; ACVRL1; BMPR1A; BMPR1B; BMPR2; TGFBR1;
References
- ↑ "Signal transduction by members of the transforming growth factor-beta superfamily". Cytokine Growth Factor Rev. 7 (4): 327–339. 1996. doi:10.1016/S1359-6101(96)00042-1. PMID 9023056.
- ↑ "Mechanism of activation of the TGF-beta receptor". Nature 370 (6488): 341–347. 1994. doi:10.1038/370341a0. PMID 8047140.
- ↑ "Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals". Cancer Surv. 27: 41–64. 1996. PMID 8909794.
External links
- Activin+receptors at the US National Library of Medicine Medical Subject Headings (MeSH)
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