Biology:Sialidase-4

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.[1]

Function

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids.[1]

Interactions

Sialidase-4 has been shown to interact with phospholipid scramblase 1.[2]

References

  1. 1.0 1.1 "Entrez Gene: NEU4 sialidase 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=129807. 
  2. "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode2005Natur.437.1173R. 

Further reading