Biology:T2-induced deoxynucleotide kinase
From HandWiki
| T2-induced deoxynucleotide kinase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.7.4.12 | ||||||||
| CAS number | 37278-99-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a T2-induced deoxynucleotide kinase (EC 2.7.4.12) is an enzyme that catalyzes the chemical reaction
- ATP + dGMP (or dTMP) [math]\displaystyle{ \rightleftharpoons }[/math] ADP + dGDP (or dTDP)
The 3 substrates of this enzyme are ATP, dGMP, and dTMP, whereas its 3 products are ADP, dGDP, and dTDP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)NMP phosphotransferase.
References
- "The enzymology of virus-infected bacteria. IV. Purification and properties of the deoxynucleotide kinase induced by bacteriophage T2". J. Biol. Chem. 238: 1777–87. 1963. PMID 13967158.
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