Biology:GABRQ
From HandWiki
Short description: Protein-coding gene in humans
 Generic protein structure example |
Gamma-aminobutyric acid receptor subunit theta is a protein that in humans is encoded by the GABRQ gene.[1][2] The protein encoded by this gene is a subunit of the GABAA receptor.
The θ subunit has highest sequence similarity with the β1 subunit.[2] This subunit coassembles with:
References
- ↑ "GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus". J. Neurosci. 20 (10): 3588–3595. 15 May 2000. doi:10.1523/jneurosci.20-10-03588.2000. PMID 10804200.
- ↑ 2.0 2.1 2.2 "θ, a novel γ-aminobutyric acid type A receptor subunit". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9891–9896. August 1999. doi:10.1073/pnas.96.17.9891. PMID 10449790. Bibcode: 1999PNAS...96.9891B.
- ↑ 3.0 3.1 "Impact of ε and θ subunits on pharmacological properties of α3β1 GABAA receptors expressed in Xenopus oocytes". BMC Pharmacol. 6: 1. 2006. doi:10.1186/1471-2210-6-1. PMID 16412217.
Further reading
- "Molecular and functional diversity of the expanding GABA-A receptor gene family". Ann. N. Y. Acad. Sci. 868 (1): 645–653. 1999. doi:10.1111/j.1749-6632.1999.tb11341.x. PMID 10414349. Bibcode: 1999NYASA.868..645W.
- "Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype". Mol. Psychiatry 15 (2): 146–153. 2010. doi:10.1038/mp.2008.66. PMID 19078961.
- "GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus". J. Neurosci. 20 (10): 3588–3595. 2000. doi:10.1523/jneurosci.20-10-03588.2000. PMID 10804200.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment". Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6): 808–816. 2009. doi:10.1002/ajmg.b.30902. PMID 19086053.
- "θ, a novel γ-aminobutyric acid type A receptor subunit". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9891–9896. 1999. doi:10.1073/pnas.96.17.9891. PMID 10449790. Bibcode: 1999PNAS...96.9891B.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Investigation of Gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility". BMC Med. Genet. 9: 109. 2008. doi:10.1186/1471-2350-9-109. PMID 19087248.
- "Genetical genomic determinants of alcohol consumption in rats and humans". BMC Biol. 7: 70. 2009. doi:10.1186/1741-7007-7-70. PMID 19874574.
External links
- GABRQ+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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