Biology:D-glycero-alpha-D-manno-heptose-7-phosphate kinase

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D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Identifiers
EC number2.7.1.168
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

D-glycero-alpha-D-manno-heptose-7-phosphate kinase (EC 2.7.1.168, D-alpha-D-heptose-7-phosphate kinase, hdda (gene)) is an enzyme with systematic name ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction

D-glycero-alpha-D-manno-heptose 7-phosphate + ATP [math]\displaystyle{ \rightleftharpoons }[/math] D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP

The enzyme participates in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.

References

  1. "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry 276 (24): 20935–44. June 2001. doi:10.1074/jbc.m100378200. PMID 11279237. 
  2. "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology 148 (Pt 7): 1979–89. July 2002. doi:10.1099/00221287-148-7-1979. PMID 12101286. 

External links