Biology:Nucleoside phosphotransferase
From HandWiki
nucleoside phosphotransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.7.1.77 | ||||||||
CAS number | 9055-37-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a nucleoside phosphotransferase (EC 2.7.1.77) is an enzyme that catalyzes the chemical reaction
- a nucleotide + a 2'-deoxynucleoside [math]\displaystyle{ \rightleftharpoons }[/math] a nucleoside + a 2'-deoxynucleoside 5'-phosphate
Thus, the two substrates of this enzyme are nucleotide and 2'-deoxynucleoside, whereas its two products are nucleoside and 2'-deoxynucleoside 5'-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is nucleotide:nucleoside 5'-phosphotransferase. Other names in common use include nonspecific nucleoside phosphotransferase, and nucleotide:3'-deoxynucleoside 5'-phosphotransferase.
References
- "Purification and properties of a nucleoside phosphotransferase from carrot". J. Biol. Chem. 242 (20): 4834–40. 1967. PMID 6061424.
- "Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme". J. Biol. Chem. 257 (9): 4931–9. 1982. PMID 6279651.
Original source: https://en.wikipedia.org/wiki/Nucleoside phosphotransferase.
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