Biology:Pseudaminic acid cytidylyltransferase

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Pseudaminic acid cytidylyltransferase
Identifiers
EC number2.7.7.81
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Pseudaminic acid cytidylyltransferase (EC 2.7.7.81, PseF) is an enzyme with systematic name CTP:5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid cytidylyltransferase.[1] This enzyme catalyses the following chemical reaction

CTP + 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + CMP-5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid

Mg2+ is required for activity.

References

  1. "Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction". Glycobiology 16 (9): 8C-14C. September 2006. doi:10.1093/glycob/cwl010. PMID 16751642. 

External links