Chemistry:2,4,5-Trihydroxymethamphetamine
From HandWiki
Revision as of 02:19, 21 September 2021 by imported>StanislovAI (linkage)
| |
| Names | |
|---|---|
| Preferred IUPAC name
5-[2-(Methylamino)propyl]benzene-1,2,4-triol | |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
| |
| |
| Properties | |
| C10H15NO3 | |
| Molar mass | 197.234 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
2,4,5-Trihydroxymethamphetamine (THMA) is a neurotoxin and a metabolite of MDMA. It has structural similarity to the dopamine neurotoxin 6-hydroxydopamine, and produces lasting serotonin deficits when administered centrally.[1][2]
See also
References
- ↑ Ikram Elayan; James W. Gibb; Glen R. Hanson; Rodger L. Foltza; Heng Keang Lima; Michel Johnson (1992). "Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine but not by 2-hydroxy-4,5-methylenedioxymethamphetamine or2-hydroxy-4,5-methylenedioxyamphetamine". European Journal of Pharmacology 221 (2–3): 281–288. doi:10.1016/0014-2999(92)90714-F. PMID 1358654.
- ↑ Anne Neudörffer; Melanie Mueller; Claire-Marie Martinez; Annis Mechan; Una McCann; George A. Ricaurte; Martine Largeron (2011). "Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and its 6-(N-Acetylcystein-S-yl) Conjugate". Chem Res Toxicol 24 (6): 968–978. doi:10.1021/tx2001459. PMID 21557581.
 |  |
