Chemistry:Toxopyrimidine

Toxopyrimidine
Names
	Preferred IUPAC name (4-Amino-2-methylpyrimidin-5-yl)methanol
	Other names Pyramin
Identifiers
CAS Number	73-67-6;
3D model (JSmol)	Interactive image;
ChemSpider	756;
PubChem CID	777;
UNII	G62V17J09J;
	InChI InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9) Key: VUTBELPREDJDDH-UHFFFAOYSA-N;
	SMILES Cc1ncc(c(n1)N)CO;
Properties
Chemical formula	C6H9N3O
Molar mass	139.158 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Toxopyrimidine is a vitamin B₆ antagonist with potent convulsant effects.^[2]^[3]

References

↑ "Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate". The Biochemical Journal 70 (4): 660–5. December 1958. doi:10.1042/bj0700660. PMID 13607425.
↑ "The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine". Nature 183 (4661): 608–9. February 1959. doi:10.1038/183608a0. PMID 13632808. Bibcode: 1959Natur.183..608R.
↑ "Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain". Nature 183 (4668): 1126–7. April 1959. doi:10.1038/1831126a0. PMID 13657025. Bibcode: 1959Natur.183.1126R.

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v t e Neurotoxins
Animal	Batrachotoxin Bestoxin Birtoxin Bungarotoxin Charybdotoxin Conotoxin Fasciculin Huwentoxin Poneratoxin Saxitoxin Tetrodotoxin Vanillotoxin Spooky toxin (SsTx) Epibatidine Zetekitoxin AB Dendrotoxin
Bacterial	Botulinum toxin Tetanospasmin
Cyanotoxins	Anatoxin-a Anatoxin-a(S) BMAA Saxitoxin
Plant	Bicuculline Penitrem A Picrotoxin Strychnine Tutin Rotenone Ginkgotoxin Cicutoxin Oenanthotoxin Thujone Volkensin
Mycotoxins	Ibotenic acid Muscarine Muscimol
Pesticides	Fenpropathrin Tetramethylenedisulfotetramine Bromethalin Crimidine Methamidophos Endosulfan Fipronil Phenylsilatrane Chlorophenylsilatrane Sulfuryl fluoride Mipafox Schradan Dimefox
Nerve agents	Cyclosarin EA-3148 Novichok agent Sarin Soman Tabun VE VG VM VP VR VX GV EA-3990 EA-4056 T-1123 Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide) Fluorotabun Chinese VX EA-2192
Bicyclic phosphates	TBPS TBPO IPTBO
Other	Dimethylmercury Toxopyrimidine IDPN

v t e Convulsants
GABA receptor antagonists	Picrotoxin Gabazine Tetramethylenedisulfotetramine Cicutoxin Phenylsilatrane Tutin Pentylenetetrazol Thujone Endosulfan Bicuculline Oenanthotoxin Fipronil EBOB BIDN Dihydropicrotoxinin DMCM FG-7142 Chlorophenylsilatrane Bicyclic phosphates (TBPS, TBPO, IPTBO)
GABA synthesis inhibitors	Allylglycine Crimidine Ginkgotoxin Toxopyrimidine Isoniazid 3-Mercaptopropionic acid 4-Deoxypyridoxine
Glycine receptor antagonists	Strychnine Tutin Picrotoxin Dendrobine
Glutamate receptor agonists	AMPA NMDA Kainic acid Domoic acid Quisqualic acid Tetrazolylglycine
Other	Methyl fluoroacetate Fluoroethyl fluoroacetate Nitrocyclohexane Methionine sulfoximine

Names


Preferred IUPAC name (4-Amino-2-methylpyrimidin-5-yl)methanol
Other names Pyramin^[1]
Identifiers
CAS Number	73-67-6
3D model (JSmol)	Interactive image
ChemSpider	756
PubChem CID	777
UNII	G62V17J09J
InChI InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9) Key: VUTBELPREDJDDH-UHFFFAOYSA-N
SMILES Cc1ncc(c(n1)N)CO
Properties
Chemical formula	C₆H₉N₃O
Molar mass	139.158 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references