Chemistry:Schradan
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Names | |
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Preferred IUPAC name
Octamethyldiphosphoric tetraamide | |
Other names
OMPA, Octamethyl pyrophosphoramide
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
EC Number |
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KEGG | |
PubChem CID
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RTECS number |
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UNII | |
UN number | 3018 |
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Properties | |
C8H24N4O3P2 | |
Molar mass | 286.253 g·mol−1 |
Density | 1.09 |
Hazards | |
Main hazards | Toxic |
GHS pictograms | |
GHS Signal word | Danger |
H300, H310, H330, H371, H373, H412 | |
P260, P262, P264, P270, P271, P273, P280, P284, P301+310, P302+350, P304+340, P309+311, P310, P314, P320, P321, P322, P330, P361, P363, P403+233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Schradan, named after Gerhard Schrader, is an obsolete organophosphate insecticide.[1] Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active.[2]
See also
References
- ↑ GARDINER, JE; KILBY, BA (April 1952). "Biochemistry of organic phosphorus insecticides. I. The mammalian metabolism of bis(dimethylamino) phosphonous anhydride (Schradan).". The Biochemical Journal 51 (1): 78–85. doi:10.1042/bj0510078. PMID 14944535.
- ↑ DAVISON, AN (October 1955). "The conversion of schra dan (OMPA) and parathion into inhibitors of cholinesterase by mammalian liver.". The Biochemical Journal 61 (2): 203–9. doi:10.1042/bj0610203. PMID 13260199.
Original source: https://en.wikipedia.org/wiki/Schradan.
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