Biology:(deoxy)adenylate kinase
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Short description: Class of enzymes
| (deoxy)adenylate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.4.11 | ||||||||
| CAS number | 37278-19-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a (deoxy)adenylate kinase (EC 2.7.4.11) is an enzyme that catalyzes the chemical reaction
- ATP + dAMP [math]\displaystyle{ \rightleftharpoons }[/math] ADP + dADP
Thus, the two substrates of this enzyme are ATP and dAMP, whereas its two products are ADP and dADP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)AMP phosphotransferase. This enzyme participates in purine metabolism.
References
- "The partial purification of deoxynucleoside monophosphate kinases from L cells". Biochim. Biophys. Acta 108 (1): 114–24. 1965. doi:10.1016/0005-2787(65)90113-9. PMID 5862227.
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