Biology:5-dehydro-2-deoxygluconokinase
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Short description: Class of enzymes
| 5-dehydro-2-deoxygluconokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.92 | ||||||||
| CAS number | 62213-35-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) is an enzyme that catalyzes the chemical reaction
- ATP + 5-dehydro-2-deoxy-D-gluconate [math]\displaystyle{ \rightleftharpoons }[/math] ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate
Thus, the two substrates of this enzyme are ATP and 5-dehydro-2-deoxy-D-gluconate, whereas its two products are ADP and 6-phospho-5-dehydro-2-deoxy-D-gluconate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase. Other names in common use include 5-keto-2-deoxygluconokinase, 5-keto-2-deoxyglucono kinase (phosphorylating), and DKH kinase. This enzyme participates in inositol metabolism.
References
- "The pathway of myo-inositol degradation in Aerobacter aerogenes Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates". J. Biol. Chem. 246 (18): 5662–75. 1971. PMID 4328832.
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