Biology:Acylglycerol kinase
From HandWiki
Short description: Class of enzymes
| acylglycerol kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.94 | ||||||||
| CAS number | 62213-37-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an acylglycerol kinase (EC 2.7.1.94) is an enzyme that catalyzes the chemical reaction
- ATP + acylglycerol [math]\displaystyle{ \rightleftharpoons }[/math] ADP + acyl-sn-glycerol 3-phosphate
The two substrates of this enzyme are ATP and acylglycerol, whereas its two products are ADP and acyl-sn-glycerol 3-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:acylglycerol 3-phosphotransferase. Other names in common use include monoacylglycerol kinase, monoacylglycerol kinase (phosphorylating), sn-2-monoacylglycerol kinase, MGK, monoglyceride kinase, and monoglyceride phosphokinase. This enzyme participates in glycerolipid metabolism.
References
- "Biosynthesis of lysophosphatdic acid from monoglyceride and adenosine triphosphate". The Journal of Biological Chemistry 237: 653–8. March 1962. PMID 14486486.
- "The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia coli" (PDF). The Journal of Biological Chemistry 240 (7): 2833–8. July 1965. PMID 14342303. http://www.jbc.org/content/240/7/2833.full.pdf.
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