Biology:Auxiliary Activity family 9
| Auxiliary Activity Family 9 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Aux_Act_9 | ||||||||
| Pfam | PF03443 | ||||||||
| InterPro | IPR005103 | ||||||||
| CAZy | AA9 | ||||||||
| |||||||||
Auxiliary Activity family 9 (formerly GH61) is a family of lytic polysaccharide monooxygenases. The family was previously incorrectly classified as glycoside hydrolase family 61, however it was re-classified in March 2013.[1][2]
AA9 is known to be a copper dependent, oxidative enzyme able to cleave crystalline cellulose.[3] Activity greatly depends on the presence of a divalent copper ion and a reductant such as gallate or ascorbate. The oxidative action of AA9 can work on either the reducing or the non-reducing end of glucose moieties.[citation needed] Although AA9 enzymes can be found in a large spectrum of biomass degrading fungi, research into this family is relatively new.[4] This classification is available on the CAZy web site,[5][6] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[7][8][9]
References
- ↑ Levasseur, Anthony; Drula, Elodie; Lombard, Vincent; Coutinho, Pedro M.; Henrissat, Bernard (2013-03-21). "Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes". Biotechnology for Biofuels 6 (1): 41. doi:10.1186/1754-6834-6-41. ISSN 1754-6834. PMID 23514094.
- ↑ Hemsworth, Glyn R; Davies, Gideon J; Walton, Paul H (2013). "Recent insights into copper-containing lytic polysaccharide mono-oxygenases". Current Opinion in Structural Biology 23 (5): 660–668. doi:10.1016/j.sbi.2013.05.006. PMID 23769965.
- ↑ Vaaje-Kolstad, Gustav; Westereng, Bjørge; Horn, Svein J.; Liu, Zhanliang; Zhai, Hong; Sørlie, Morten; Eijsink, Vincent G. H. (2010-10-08). "An Oxidative Enzyme Boosting the Enzymatic Conversion of Recalcitrant Polysaccharides" (in en). Science 330 (6001): 219–222. doi:10.1126/science.1192231. ISSN 0036-8075. PMID 20929773. Bibcode: 2010Sci...330..219V.
- ↑ Bey, Mathieu; Zhou, Simeng; Poidevin, Laetitia; Henrissat, Bernard; Coutinho, Pedro M.; Berrin, Jean-Guy; Sigoillot, Jean-Claude (2013-01-15). "Cello-Oligosaccharide Oxidation Reveals Differences between Two Lytic Polysaccharide Monooxygenases (Family GH61) from Podospora anserina" (in en). Applied and Environmental Microbiology 79 (2): 488–496. doi:10.1128/aem.02942-12. ISSN 0099-2240. PMID 23124232. Bibcode: 2013ApEnM..79..488B.
- ↑ "Home" (in en). http://www.cazy.org/.
- ↑ "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research 42 (Database issue): D490–5. January 2014. doi:10.1093/nar/gkt1178. PMID 24270786.
- ↑ "Auxiliary Activity Family 9" (in en). http://www.cazypedia.org/index.php/Auxiliary_Activity_Family_9.
- ↑ "Glycoside Hydrolase Family 61" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_61.
- ↑ CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. PMID 29040563. https://hal.archives-ouvertes.fr/hal-01886461/file/Hehemann_2018_01.pdf.
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