Biology:Beta-amyrin 24-hydroxylase

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Beta-amyrin 24-hydroxylase
Identifiers
EC number1.14.99.43
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Beta-amyrin 24-hydroxylase (EC 1.14.99.43, sophoradiol 24-hydroxylase, CYP93E1) is an enzyme with systematic name beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating).[1] This enzyme catalyses the following chemical reaction

(1) beta-amyrin + AH2 + O2 [math]\displaystyle{ \rightleftharpoons }[/math] 24-hydroxy-beta-amyrin + A + H2O
(2) sophoradiol + AH2 + O2 [math]\displaystyle{ \rightleftharpoons }[/math] 24-hydroxysophoradiol + A + H2O

Beta-amyrin 24-hydroxylase is heme-thiolate protein (P-450).

References

  1. "Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay". The FEBS Journal 273 (5): 948–59. March 2006. doi:10.1111/j.1742-4658.2006.05120.x. PMID 16478469. 

External links