Biology:CDP-glycerol glycerophosphotransferase

From HandWiki
CDP-glycerol glycerophosphotransferase
Identifiers
EC number2.7.8.12
CAS number9076-71-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a CDP-glycerol glycerophosphotransferase (EC 2.7.8.12) is an enzyme that catalyzes the chemical reaction

CDP-glycerol + (glycerophosphate)n [math]\displaystyle{ \rightleftharpoons }[/math] CMP + (glycerophosphate)n+1

Thus, the two substrates of this enzyme are CDP-glycerol and (glycerophosphate)n, whereas its two products are CMP and (glycerophosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase. Other names in common use include teichoic-acid synthase, cytidine diphosphoglycerol glycerophosphotransferase, poly(glycerol phosphate) polymerase, teichoic acid glycerol transferase, glycerophosphate synthetase, and CGPTase.

References

  • "THE SYNTHESIS OF TEICHOIC ACIDS. I. POLYGLYCEROPHOSPHATE". J. Biol. Chem. 239: 3168–77. 1964. PMID 14245357.