Biology:CYP53 family
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Short description: Group of cytochrome P450 enzymes
Cytochrome P450, family 53, also known as CYP53, is a cytochrome P450 monooxygenase family in fungi related to hydrocarbon assimilation.[1] They are distributed in both Ascomycota and Basidiomycota, could be used as anti-fungal drug target.[2] The first gene identified in this family is the CYP53A1 from Aspergillus niger encoding the Benzoate 4-monooxygenase (bphA).[3]
References
- ↑ "Insights into Hydrocarbon Assimilation by Eurotialean and Hypocrealean Fungi: Roles for CYP52 and CYP53 Clans of Cytochrome P450 Genes". Applied Biochemistry and Biotechnology 184 (3): 1047–1060. March 2018. doi:10.1007/s12010-017-2608-z. PMID 28942502. http://sedici.unlp.edu.ar/handle/10915/141006.
- ↑ "Cytochrome P450 monooxygenase CYP53 family in fungi: comparative structural and evolutionary analysis and its role as a common alternative anti-fungal drug target". PLOS ONE 9 (9): e107209. 2014. doi:10.1371/journal.pone.0107209. PMID 25222113. Bibcode: 2014PLoSO...9j7209J.
- ↑ "Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger". Archives of Biochemistry and Biophysics 394 (2): 245–54. October 2001. doi:10.1006/abbi.2001.2534. PMID 11594739.
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