Biology:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
From HandWiki
| D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.70 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase (EC 2.7.7.70, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-glycero-D-manno-heptose-1beta-phosphate adenylyltransferase, hldE (gene), rfaE (gene)) is an enzyme with systematic name ATP:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- D-glycero-beta-D-manno-heptose 1-phosphate + ATP [math]\displaystyle{ \rightleftharpoons }[/math] ADP-D-glycero-beta-D-manno-heptose + diphosphate
The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose.
References
- ↑ "The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose". Journal of Bacteriology 182 (2): 488–97. January 2000. doi:10.1128/jb.182.2.488-497.2000. PMID 10629197.
- ↑ "Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli". Journal of Bacteriology 184 (2): 363–9. January 2002. doi:10.1128/jb.184.2.363-369.2002. PMID 11751812.
- ↑ "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology 148 (Pt 7): 1979–89. July 2002. doi:10.1099/00221287-148-7-1979. PMID 12101286.
- ↑ "Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB)". Biochemistry 49 (6): 1072–81. February 2010. doi:10.1021/bi902018y. PMID 20050615.
External links
- D-glycero-beta-D-manno-heptose+1-phosphate+adenylyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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