Biology:Dolichyl-diphosphate—polyphosphate phosphotransferase

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dolichyl-diphosphate-polyphosphate phosphotransferase
Identifiers
EC number2.7.4.20
CAS number94949-27-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a dolichyl-diphosphate-polyphosphate phosphotransferase (EC 2.7.4.20) is an enzyme that catalyzes the chemical reaction

dolichyl diphosphate + (phosphate)n [math]\displaystyle{ \rightleftharpoons }[/math] dolichyl phosphate + (phosphate)n+1

Thus, the two substrates of this enzyme are dolichyl diphosphate and (phosphate)n, whereas its two products are dolichyl phosphate and (phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is dolichyl-diphosphate:polyphosphate phosphotransferase. This enzyme is also called dolichylpyrophosphate:polyphosphate phosphotransferase.

References

  • "Two pathways of dephosphorylation of dolichyl diphosphate in yeasts". Biochemistry (Moscow) 50: 551–556.