Biology:Erythritol kinase

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erythritol kinase
Identifiers
EC number2.7.1.27
CAS number9030-64-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an erythritol kinase (EC 2.7.1.27) is an enzyme that catalyzes the chemical reaction

ATP + erythritol [math]\displaystyle{ \rightleftharpoons }[/math] ADP + D-erythritol 4-phosphate

Thus, the two substrates of this enzyme are ATP and erythritol, whereas its two products are ADP and D-erythritol 4-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:erythritol 4-phosphotransferase. This enzyme is also called erythritol kinase (phosphorylating).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V5S.

References

  • "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. 1961. PMID 13908588. 
  • "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. 1961. PMID 13908588.