Biology:Hygromycin-B kinase

From HandWiki
hygromycin B kinase
Identifiers
EC number2.7.1.119
CAS number88361-67-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a hygromycin-B kinase (EC 2.7.1.119) is an enzyme that catalyzes the chemical reaction

ATP + hygromycin B [math]\displaystyle{ \rightleftharpoons }[/math] ADP + 7"-O-phosphohygromycin

Thus, the two substrates of this enzyme are ATP and hygromycin B, whereas its two products are ADP and 7-O-phosphohygromycin.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:hygromycin-B 7"-O-phosphotransferase. This enzyme is also called hygromycin B phosphotransferase.

References