Biology:Klebsiella granulomatis
| Klebsiella granulomatis | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Gammaproteobacteria |
| Order: | Enterobacterales |
| Family: | Enterobacteriaceae |
| Genus: | Klebsiella |
| Species: | K. granulomatis
|
| Binomial name | |
| Klebsiella granulomatis (Aragão and Vianna 1913) Carter et al. 1999
| |
Klebsiella granulomatis is Gram-negative, rod-shaped bacterium of the genus Klebsiella[1] known to cause the sexually transmitted disease granuloma inguinale (or donovanosis). It was formerly called Calymmatobacterium granulomatis.[2]
It is a stationary aerobic bacillus with non-sporulated capsule measuring 0.5 to 2.0 μm.[3][4] It has biochemical properties such as catalase positive, phenylalanine negative and citrate positive with hydrolysis in urea.[5] Among its virulence factors are its capsule, endotoxins, siderophores, antimicrobial resistance and antigenic phase variation.[6]
Incubation period
The incubation period lasts around 50 days, may vary between 1 and 12 weeks.[7]
Epidemiology
This rare form of genital ulceration is about to be eradicated worldwide. There are currently alarming figures in areas such as India , Papua New Guinea, the Caribbean, South America, Zambia, Zimbabwe, South Africa and Australia .[8]
Thanks to the recognition as a public health problem and appropriate control measures such as the implementation of better health service provisions, the incidence of this microorganism in countries such as Papua New Guinea, South Africa , India and the Caribbean has decreased significantly.[8]
References
- ↑ Sherris Medical Microbiology (4th ed.). McGraw Hill. 2004. p. 370. ISBN 978-0-8385-8529-0.
- ↑ "Donovanosis". Sexually Transmitted Infections 78 (6): 452–7. December 2002. doi:10.1136/sti.78.6.452. PMID 12473810.
- ↑ "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourinary Medicine 67 (6): 441–52. December 1991. doi:10.1136/sti.67.6.441. PMID 1774048.
- ↑ "Hypertrophic donavanosis in a young pregnant woman" (in English). Journal of Pediatric and Adolescent Gynecology 25 (4): e81-3. August 2012. doi:10.1016/j.jpag.2011.10.002. PMID 22840941. https://www.jpagonline.org/article/S1083-3188(11)00387-1/abstract.
- ↑ "Donovanosis, case repor t". Revista Mexicana de Coloproctologí 13: 59–65. May 2007. https://www.medigraphic.com/pdfs/proctologia/c-2007/c072e.pdf.
- ↑ Stoner, Bradley P. (2018-01-01). "Klebsiella granulomatis: Granuloma Inguinale". in Long, Sarah S.; Prober, Charles G.; Fischer, Marc. Principles and Practice of Pediatric Infectious Diseases (fifth ed.). Elsevier. pp. 823–824.e1. doi:10.1016/b978-0-323-40181-4.00139-0. ISBN 978-0-323-40181-4. http://www.sciencedirect.com/science/article/pii/B9780323401814001390.
- ↑ "Protocolo diagnóstico y terapéutico de las úlceras genitales" (in Spanish). Medicine - Programa de Formación Médica Continuada Acreditado. Enfermedades infecciosas (III): Infecciones por espiroquetas, borrelias, chlamydias y micoplasmas 11 (51): 3024–3028. 2014-03-01. doi:10.1016/S0304-5412(14)70733-4.
- ↑ 8.0 8.1 "Calymmatobacterium Granulomatis Infections". xPharm: The Comprehensive Pharmacology Reference. Elsevier. January 2007. pp. 1–4. doi:10.1016/b978-008055232-3.60880-3. ISBN 978-0-08-055232-3.
External links
- "Klebsiella granulomatis". NCBI Taxonomy Browser. https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=39824.
Wikidata ☰ Q150946 entry
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