Biology:MT-TA
From HandWiki
Short description: Transfer RNA
 Generic protein structure example |
Mitochondrially encoded tRNA alanine also known as MT-TA is a transfer RNA, which in humans is encoded by the mitochondrial MT-TA gene.[1]
MT-TA is a small 69 nucleotide RNA (human mitochondrial map position 5587-5655) that transfers the amino acid alanine to a growing polypeptide chain at the ribosome site of protein synthesis during translation.
It has been reported that the 5650G-A mutation on MT-TA may cause muscular dystrophy.[2]
References
- ↑ "Sequence and organization of the human mitochondrial genome". Nature 290 (5806): 457–65. April 1981. doi:10.1038/290457a0. PMID 7219534. Bibcode: 1981Natur.290..457A.
- ↑ Horvath, R (2003). "A tRNAAla mutation causing mitochondrial myopathy clinically resembling myotonic dystrophy". Journal of Medical Genetics 40 (10): 752–757. doi:10.1136/jmg.40.10.752. ISSN 1468-6244. PMID 14569122.
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