Biology:Pentalenic acid synthase
From HandWiki
| Pentalenic acid synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.14.15.11 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Pentalenic acid synthase (EC 1.14.15.11, CYP105D7, sav7469 (gene)) is an enzyme with systematic name 1-deoxypentalenate,reduced ferredoxin:O2 oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- 1-deoxypentalenate + reduced ferredoxin + O2 [math]\displaystyle{ \rightleftharpoons }[/math] pentalenate + oxidized ferredoxin + H2O
Pentalenic acid synthase is a heme-thiolate enzyme (P-450).
References
- ↑ "Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis". The Journal of Antibiotics 64 (1): 65–71. January 2011. doi:10.1038/ja.2010.135. PMID 21081950.
External links
- Pentalenic+acid+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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