Biology:Phosphoribokinase
From HandWiki
| phosphoribokinase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.7.1.18 | ||||||||
| CAS number | 9030-59-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a phosphoribokinase (EC 2.7.1.18) is an enzyme that catalyzes the chemical reaction
- ATP + D-ribose 5-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] ADP + D-ribose 1,5-bisphosphate
Thus, the two substrates of this enzyme are ATP and D-ribose 5-phosphate, whereas its two products are ADP and D-ribose 1,5-bisphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-ribose-5-phosphate 1-phosphotransferase. This enzyme is also called phosphoribokinase (phosphorylating).
References
- Phosphorylase b kinase from rabbit muscle. Methods in Enzymology. 8. 1966. pp. 543–546. doi:10.1016/0076-6879(66)08097-2. ISBN 978-0-12-181808-1.
- "The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides". Biochimica et Biophysica Acta 12 (1–2): 250–64. 1953. doi:10.1016/0006-3002(53)90144-9. PMID 13115434.
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