Biology:Streptomycin 3"-adenylyltransferase
| streptomycin 3"-adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.47 | ||||||||
| CAS number | 52660-23-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a streptomycin 3"-adenylyltransferase (EC 2.7.7.47) is an enzyme that catalyzes the chemical reaction:
- ATP + streptomycin [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + 3"-adenylylstreptomycin
Thus, the two substrates of this enzyme are ATP and streptomycin, whereas its two products are diphosphate and 3-adenylylstreptomycin.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:streptomycin 3"-adenylyltransferase. Other names in common use include streptomycin adenylate synthetase, streptomycin adenyltransferase, streptomycin adenylylase, streptomycin adenylyltransferase, streptomycin-spectinomycin adenylyltransferase, AAD (3"), and aminoglycoside 3"-adenylyltransferase.
References
- "Resistance factor-mediated streptomycin resistance". J. Bacteriol. 97 (3): 1262–71. 1969. PMID 4887506.
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