Biology:Sulfate adenylyltransferase (ADP)
From HandWiki
| sulfate adenylyltransferase (ADP) | |||||||||
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| Identifiers | |||||||||
| EC number | 2.7.7.5 | ||||||||
| CAS number | 9027-70-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a sulfate adenylyltransferase (ADP) (EC 2.7.7.5) is an enzyme that catalyzes the chemical reaction
- ADP + sulfate [math]\displaystyle{ \rightleftharpoons }[/math] phosphate + adenylyl sulfate
Thus, the two substrates of this enzyme are ADP and sulfate, whereas its two products are phosphate and adenylyl sulfate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:sulfate adenylyltransferase. Other names in common use include ADP-sulfurylase, sulfate (adenosine diphosphate) adenylyltransferase, and adenosine diphosphate sulfurylase. This enzyme participates in sulfur metabolism.
References
- "[Yeast ADP-sulfurylase catalyzing an exchange between orthophosphate and the terminal phosphate of nucleoside diphosphates]". Biochim. Biophys. Acta 123 (1): 1–16. 1966. doi:10.1016/0005-2787(66)90153-5. PMID 5964041.
- "Isolation and identification of active sulfate". J. Biol. Chem. 229 (2): 837–51. 1957. PMID 13502346.
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