Biology:Triphosphoribosyl-dephospho-CoA synthase

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triphosphoribosyl-dephospho-CoA synthase
Identifiers
EC number2.7.8.25
CAS number313345-38-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a triphosphoribosyl-dephospho-CoA synthase (EC 2.7.8.25) is an enzyme that catalyzes the chemical reaction

ATP + 3-dephospho-CoA [math]\displaystyle{ \rightleftharpoons }[/math] 2'-(5"-triphosphoribosyl)-3'-dephospho-CoA + adenine

Thus, the two substrates of this enzyme are ATP and 3-dephospho-CoA, whereas its two products are 2'-(5-triphosphoribosyl)-3'-dephospho-CoA and adenine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is ATP:3-dephospho-CoA 5"-triphosphoribosyltransferase. Other names in common use include 2'-(5"-triphosphoribosyl)-3-dephospho-CoA synthase, ATP:dephospho-CoA 5-triphosphoribosyl transferase, and CitG. This enzyme participates in two-component system - general.

References