Biology:UTP-monosaccharide-1-phosphate uridylyltransferase
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Short description: Class of enzymes
| UTP-monosaccharide-1-phosphate uridylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.64 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, an UTP-monosaccharide-1-phosphate uridylyltransferase (EC 2.7.7.64) is an enzyme that catalyzes the chemical reaction
- UTP + a monosaccharide 1-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + UDP-monosaccharide
Thus, the two substrates of this enzyme are UTP and monosaccharide 1-phosphate, whereas its two products are diphosphate and UDP-monosaccharide.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is '. Other names in common use include UDP-sugar pyrophosphorylase', and PsUSP.
References
- Tsumuraya Y; Yamaguchi, D; Ohzono, H; Hojo, S; Kaneko, S; Ishida, HK; Tsumuraya, Y (2004). "UDP-sugar pyrophosphorylase with broad substrate specificity toward various monosaccharide 1-phosphates from pea sprouts". J. Biol. Chem. 279 (44): 45728–36. doi:10.1074/jbc.M408716200. PMID 15326166.
- "Uridine diphosphate glucose pyrophosphorylase of Acanthamoeba castellanii. Purification, kinetic, and developmental studies". J. Biol. Chem. 249 (24): 7832–40. 1974. PMID 4430676.
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