Biology:ATP adenylyltransferase
| ATP adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.53 | ||||||||
| CAS number | 96697-71-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an ATP adenylyltransferase (EC 2.7.7.53) is an enzyme that catalyzes the chemical reaction
- ADP + ATP [math]\displaystyle{ \rightleftharpoons }[/math] phosphate + P1,P4-bis(5'-adenosyl) tetraphosphate
Thus, the two substrates of this enzyme are ADP and ATP, whereas its two products are phosphate and P1,P4-bis(5'-adenosyl) tetraphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:ATP adenylyltransferase. Other names in common use include bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosinetetraphosphate alphabeta-phosphorylase, adenine triphosphate adenylyltransferase, diadenosine 5',5'"-P1,P4-tetraphosphate alphabeta-phosphorylase, (ADP-forming), and dinucleoside oligophosphate alphabeta-phosphorylase. This enzyme participates in purine metabolism.
References
- "Phosphorolytic cleavage of diadenosine 5',5-P1,P4-tetraphosphate Properties of homogeneous diadenosine 5',5-P1,P4-tetraphosphate alpha, beta-phosphorylase from Saccharomyces cerevisiae". J. Biol. Chem. 260 (6): 3542–7. 1985. PMID 2982863.
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