Biology:(phosphorylase) phosphatase
From HandWiki
Short description: Class of enzymes
| phosphorylase a phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.17 | ||||||||
| CAS number | 9025-74-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme phosphorylase a phosphatase (EC 3.1.3.17) catalyzes the reaction
- [phosphorylase a] + 4 H2O [math]\displaystyle{ \rightleftharpoons }[/math] 2 [phosphorylase b] + 4 phosphate
It is synonymous with Protein phosphatase 1. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is [phosphorylase a] phosphohydrolase. Other names in common use include PR-enzyme, phosphorylase a phosphatase, glycogen phosphorylase phosphatase, protein phosphatase C, and type 1 protein phosphatase.
References
- "Purification and properties of rabbit liver phosphorylase phosphatase". J. Biol. Chem. 250 (20): 8038–44. 1975. PMID 240850.
- "Specificity studies on muscle phosphorylase phosphatase". J. Biol. Chem. 235: 805–9. 1960. PMID 13829077.
- "The interconversion of phosphorylase a and phosphorylase b from dog heart muscle". Biochim. Biophys. Acta 20 (1): 69–76. 1956. doi:10.1016/0006-3002(56)90264-5. PMID 13315351.
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