Biology:Arylsulfatase

From HandWiki
Short description: Class of enzymes
Arylsulfatase
4cxs.jpg
Arylsulfatase monomer, Pseudomonas aeruginosa
Identifiers
EC number3.1.6.1
CAS number9016-17-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Arylsulfatase (EC 3.1.6.1, sulfatase, nitrocatechol sulfatase, phenolsulfatase, phenylsulfatase, p-nitrophenyl sulfatase, arylsulfohydrolase, 4-methylumbelliferyl sulfatase, estrogen sulfatase) is a type of sulfatase enzyme with systematic name aryl-sulfate sulfohydrolase.[1][2][3][4] This enzyme catalyses the following chemical reaction

an aryl sulfate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] a phenol + sulfate

Types include:

  • Arylsulfatase A (also known as "cerebroside-sulfatase")
  • Arylsulfatase B (also known as "N-acetylgalactosamine-4-sulfatase")
  • Steroid sulfatase (formerly known as "arylsulfatase C")
  • ARSC2
  • ARSD
  • ARSF
  • ARSG
  • ARSH
  • ARSI
  • ARSJ
  • ARSK
  • ARSL (formerly known as "arylsulfatase E", "ARSE")

See also

References

  1. "Studies on sulphatases. 13. The hydrolysis of substituted phenyl sulphates by the arylsulphatase of Alcaligenes metalcaligenes". The Biochemical Journal 64 (2): 216–21. October 1956. PMID 13363831. 
  2. "The synthesis and hydrolysis of sulfate esters". Advances in Enzymology and Related Subjects of Biochemistry 22: 205–35. 1960. PMID 13744184. 
  3. "Sulphatases, lysosomes and disease". The Australian Journal of Experimental Biology and Medical Science 54 (2): 111–35. April 1976. doi:10.1038/icb.1976.13. PMID 13772. 
  4. "The activation of an arysulphatase from ox liver by chloride and other anions". The Biochemical Journal 73 (1): 7–15. September 1959. PMID 13843260.