Biology:Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase

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glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
Identifiers
EC number3.1.4.51
CAS number123940-44-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase (EC 3.1.4.51) catalyzes the reaction

6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O [math]\displaystyle{ \rightleftharpoons }[/math] α-D-glucose 1-phosphate + D-mannosylglycoprotein

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase. This enzyme is also called α-glucose-1-phosphate phosphodiesterase.

References

  • "An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol". J. Biol. Chem. 264 (34): 20540–6. 1989. PMID 2555363.